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STEM PLUS

STEM PLUS - restoration and treatment at the cellular level with scientific precision

100

Number of patients

100

Number of procedures

100

Number of studies

50

Countries of work

10

Years of experience
ABOUT US

STEM PLUS — health begins at the cellular level

Cell therapy clinic and biotechnology laboratory in Bulgaria

We live in an era when health can not only be preserved, but also restored — accurately, deeply, scientifically. At STEM PLUS, we have opened a clinic and cell therapy laboratory in Bulgaria to make cutting-edge medical technologies available to those who want more than just treatment — those who choose quality of life, activity, and long-term results. Our team has over 25 years of experience in international regenerative medicine, including cell therapy, anti-aging protocols, and recovery from severe stress (stress, cancer, radiation, age-related changes). We combine:

  • our own GMP-compliant laboratory,
  • a certified stem cell bank,
  • personalized treatment protocols,
  • scientific accuracy, and evidence-based medicine.
Our products

Fibroblasts from Wharton’s Jelly of the Umbilical Cord

Fibroblasts from Wharton’s Jelly of the Umbilical Cord

Details

Fetal Stem Cells (Research Area)

Fetal Stem Cells (Research Area)

Details

MSCs (Mesenchymal Stem Cells) from Amniotic Membrane of the Placenta

MSCs (Mesenchymal Stem Cells) from Amniotic Membrane of the Placenta

Details
Our services

Treatment of diseases

Multiple sclerosis

We offer cell therapy for multiple sclerosis to reduce inflammation, support neural repair, and slow progression

Autism

Our cell therapy for autism aims to improve cognitive function, reduce inflammation, and support neural development.

Diabetes

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Muscular dystrophy

We use cell therapy to support muscle regeneration, improve strength, and slow the progression of muscular dystrophy.

Aesthetic medicine

Our cell-based solutions in aesthetic medicine promote skin regeneration, reduce signs of aging, and enhance natural rejuvenation.

Alzheimers disease

Our cell therapy for Alzheimer’s disease targets neuroinflammation, supports cognitive function, and slows neurodegeneration.

Anemia treatment

Our cell therapy for anemia supports blood cell regeneration and helps restore healthy hematopoietic function.

Arterial hypertension

Our cell therapy for arterial hypertension aims to improve vascular function and support blood pressure regulation.

Cirrhosis

Our cell therapy for cirrhosis promotes liver regeneration, reduces inflammation, and supports organ function restoration.

Cerebral palsy

Our cell therapy for cerebral palsy aims to improve motor function, reduce neuroinflammation, and support brain repair.

Erectile dysfunction

Our cell therapy for erectile dysfunction enhances vascular regeneration and supports natural erectile function.

Male infertility

Our cell therapy for male infertility aims to improve sperm quality, restore testicular function, and support hormonal balance.

Mental retardation

Our cell therapy for neurodevelopmental delay supports healthy brain development, strengthens mental activity, improves cognitive function, and enhances neural connectivity.

Parkinson disease

Our cell therapy for Parkinson’s disease supports dopamine regulation, improves motor function, and promotes neural repair.

Primary immunodeficiency

Our cell therapy for primary immunodeficiency helps restore immune balance, enhance defense mechanisms, and reduce infection risk.

Rheumatoid arthritis

Our cell therapy for rheumatoid arthritis reduces inflammation, balances immune activity, and supports joint tissue repair.

SMA

Our cell therapy for SMA aims to support motor neuron function, improve muscle strength, and slow disease progression.

Why choose us?

Our advantages

GMP-compliant laboratory

Our in-house biotechnology laboratory is designed and certified to international GMP standards. This guarantees sterility, safety, and accuracy at every stage—from cell isolation to administration.

Personalized support and guidance

We accompany patients through every stage, from the initial consultation to post-treatment follow-up. Attention to detail, care, and access to a doctor are always at hand.

Over 25 years of international experience

Our team of doctors and biotechnologists has been working in the field of cell therapy since the late 1990s. We implement best practices from Switzerland, Israel, and Germany, adapting them to the needs of each patient.

Evidence-based methods and a personalized approach

We do not treat patients according to a template. Each therapy is based on analyses, biomarkers, and epigenetic clocks. You receive a protocol tailored to your body — scientifically, accurately, and safely.

What diseases do you treat: Our services
Meet the specialists

Our doctors

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How we work

Sequence of work

Get a consultation

FAQ

General questions

Stem cells are the body’s raw materials — cells from which all other specialized cells are generated. In regenerative medicine, stem cells can help repair damaged tissues and reduce inflammation, promoting natural healing.

Stem cell therapy has shown promise in treating a wide range of conditions, including orthopedic injuries, autoimmune diseases, neurological disorders (such as multiple sclerosis), and even some chronic degenerative diseases.

Yes, when performed by qualified professionals in a controlled medical environment, stem cell therapy is generally considered safe. We use only ethically sourced, high-quality stem cells and follow strict clinical protocols.

At StemPlus, we use mesenchymal stem cells (MSCs) derived from umbilical cord tissue or adipose (fat) tissue, depending on the treatment plan. All sources are ethically obtained and rigorously screened for safety.

Results vary depending on the condition and the individual. Some patients begin to notice improvements within weeks, while others may require several months. A full assessment will be provided during your consultation.

Mild side effects such as soreness at the injection site or temporary fatigue may occur. Serious complications are rare but will be discussed in detail before your treatment to ensure informed consent.

We offer personalized consultations to determine your eligibility based on your medical history, current condition, and treatment goals. Contact us to schedule a free initial evaluation.

Address

32 Elemag St.,
Izgrev Res. Complex,
Izgrev District,
1113 Sofia, Bulgaria

Phone&Email

+359 87 7000039
office@stemplus.bg

Hours of operation

Monday - Friday
09:00 - 17:00

Stem Cell Treatment in a Clinic in the European Union, Bulgaria

Stem cells are unique cells in the body that have the ability to self-renew and transform into various types of specialized cells. Stem cells are classified into several basic types:

  • embryonic stem cells are obtained at early stages of embryonic development and have highest differentiation potential; they can be used for many purposes;
  • adult stem cells are found in body tissues and are responsible for their renewal;
  • mesenchymal stem cells are derived from bone marrow, adipose tissue or umbilical cord and have applications in regenerative medicine;
  • induced pluripotent stem cells are artificially reprogrammed adult stem cells that acquire the properties of embryonic structures.

With their ability to regenerate, stem cells play a key role in the repair of damaged tissues and open up new prospects in the fight against many diseases that were previously considered incurable or associated with high life-threatening risks.

What Are the Uses of Stem Cells in Medicine?

Stem cells are used in many areas of medicine because of their ability to differentiate and regenerate:

  1. Cardiovascular diseases. Stem cells promote the regeneration of damaged heart muscle after a heart attack, restore blood vessels and improve blood flow.
  2. Neurological disorders. Stem cells are used to treat stroke, Parkinson’s disease, Alzheimer’s disease, multiple sclerosis and other neurological diseases by helping to restore nerve cells and neural connections.
  3. Cancer. Bone marrow stem cell transplants are used to treat leukemia, lymphoma and other cancers.
  4. Injuries and Damage. Stem cells promote healing of bones, tendons, muscles and nerves after serious injuries or surgery.
  5. Degenerative diseases. Stem cells are used in the treatment of osteoarthritis and other degenerative conditions of the joints and spinal discs.

The mechanism of action of stem cells is to stimulate repair of affected tissues, reduce inflammation, improve blood supply and create favorable conditions for regeneration.

Stem Cell Treatment in a Clinic in the European Union, Bulgaria: Description of the Process and Stages

Treating various diseases in our clinic in Bulgaria is done step by step according to high European standards and protocols, which guarantees safety and best results. The process includes the following stages

  1. Diagnosis. A comprehensive medical evaluation is performed to assess the patient’s condition and the feasibility of cell therapy.
  2. Preparation. After assessing the potential risks, an individualized treatment protocol is selected.
  3. Choice of stem cell type. Autologous or donor cells are used depending on the diagnosis.
  4. Administration of stem cells. The procedure can be performed intravenously, locally or by other methods.
  5. Follow-up. After the procedure, our doctors monitor the patient’s condition and the effectiveness of the treatment.  

Our clinic provides strict control over compliance with European protocols, uses the latest technologies and an individual approach to each patient.

Advantages of Stem Cell Therapy in Bulgaria

Stem cell therapy opens new possibilities in the treatment of various conditions, providing the following benefits:

  1. Restoration of organ and tissue functions by stimulating natural regeneration processes.
  2. Improving quality of life by reducing symptoms of chronic disease and targeting causative mechanisms.
  3. Reducing the need for surgery and avoiding complex operations.
  4. Fewer side effects compared to traditional treatments.

Our clinic in Bulgaria offers treatment according to European standards, using the latest technologies. At the same time, it remains affordable for patients from the EU and other countries.

Risks and Limitations of Stem Cell Treatment

Cell therapy involves some risks, such as cell rejection, infection or procedure-related complications. However, they are minimized due to the high qualification of our doctors and modern methods.

Limitations of the method include its high cost and the need for additional research to confirm its effectiveness in certain areas.

Prospects for the Development of Cell Therapy in EU Clinics

Scientific research and clinical trials contribute to the development of stem cell treatment technologies in the European Union, including Bulgaria, and improve their safety and effectiveness. New technologies and discoveries, including improved methods of delivering cells and cell populations, can significantly improve accessibility and efficacy. Research is primarily focused on reducing costs and expanding the indications for stem cell therapy.

Applying to certified clinics in the European Union is an important step towards safe and effective stem cell treatment. Patients should be very careful in the choice of the clinic, inquire about the licenses, experience of the doctors and the equipment of the clinic. Preparation for the treatment and post-treatment monitoring are crucial for achieving positive results.

Please schedule a consultation at our clinic in Bulgaria to receive help from qualified experts in stem cell treatment and to learn about the possibility of their use in your specific clinical case.

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